Abstract: According to the concept of sustainable development，and based on the principle of maximizing the utilization of resources，through technology integration and devices innovation，a comprehensive route has been put foreword to control sewage pollution on swine farm，including the solid-liquid tank，the upflow sequencing biogas digester，the solid-liquid separator，combining with the automatic control system of large-scale biogas project． The model was applied to Xinxing Pigs Breeding Co． ，Ltd． of Fujian Province， and the results showed that: the reusing of manure resources could be come true，and the environmental pollution had been avoided． The comprehensive route was expected to establish a ecological technology model for sewage pollution controlling of large-scale swine farms．