Abstract: The discharge voltage，initial concentration of Escherichia coli，different test device were investigated while treating Escherichia coli from a wastewater treatment plant by streamer corona plasmas; and researchers compared the result of streamer corona plasmas and ozone disinfection． The results showed that the sterilization rate of Escherichia coli was 99% when initial concentration of Escherichia coli was 480 000 per litre，discharge time was 45 min，volume of water sample was 50 L，gas flow rate was 8 m3 /h，discharge voltage was 30 kV，the current was 11 mA in the tank at the room temperature; streamer corona plasmas and ozone disinfection had high sterilization capability，but the economic cost of streamer corona plasmas was cheaper than ozone disinfection．