Abstract: Climate，the basic requirement of as human survival activities and development，its change is also bound to influence the complex ecosystem combined with“social-economy-eco-environment subsystem”． At the same time，in the process of urban construction，population growth，economic development，and spatial expansion，resources such as energy consumption had some side effects on climate changes． Based on the combination of qualitative and quantitative analysis methods，the coupling relationship between indicators of climate change and urban system was established． Taking Nanjing as an example，using the Spearman correlation coefficient to construct a interaction model，the coupling relationship was revealed quantitatively．