Abstract: A list of priority control pollutants was obtained by using the improved model-based prioritization exercise for the EU Water Framework Directive ( EU WFD) ． Retrieved pollutants lists and water quality standards in the United States， European Union，Japan and other countries and regions，by preliminary analyzing and screening substances from these lists， 449 substances were registered and being used in our country． These substances were given scores by the improved modelbased prioritization exercise for the EU WFD，then were ranked according to their semi lethal toxity，in the end，a list of 19 substances were classified as sorting list of environmental priority substances． The results showed that，after supplement and screening the existing list of pollutants for WFD combined with Chinese actual situation，the method was suitable as a screening method for environmental priority pollutants，it can comprehensively screen substances with serious environmental hazards．