RESEARCH PROGRESS ON TOXICITY DETECTION INDICATORS BASED ON DIFFERENT BIOLOGICAL LEVELS
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摘要: 水质安全不仅关乎生态环境的健康发展,更与人类的生存质量息息相关。对水体进行毒性检测是保障水质安全的重要手段。从生物种类出发,总结了鱼类、藻类等受试生物的特点及适用范围;综述了在不同生物学层面上毒性的表征指标,其中以细胞水平为基础的检测方法可实现快速、在线的毒性检测。并对毒性检测今后的发展方向进行了展望。Abstract: Water quality safety is not only related to the healthy development of the ecological environment, but also closely related to the quality of human life. Toxicity testing of water bodies is an important mean to ensure the water quality. Firstly, the characteristics and application scope of the tested organisms, such as fish and algae, was introduced from the perspective of biological species in this paper. Secondly, the characterization indicators of toxicity at different biological levels were reviewed. The cell-based detection method could achieve fast and online toxicity testing. Finally, the future development direction of toxicity testing was prospected and a new research idea was provided.
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Key words:
- biology /
- toxicity testing /
- toxicity characterization index /
- on-line monitoring
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HASSAN S H A, VAN GINKEL STEVEN W, HUSSEIN M A M, et al. Toxicity assessment using different bioassays and microbial biosensors[J]. Environment International, 2016, 92/93(7/8):106-118. RASHEED T, BILAL M, NABEEL F, et al. Fluorescent sensor based models for the detection of environmentally-related toxic heavy metals[J]. Science of the Total Environment, 2018, 615(2):476-485. 王作铭, 陈军, 陈静, 等. 地表水中抗生素复合残留对水生生物的毒性及其生态风险评价[J]. 生态毒理学报, 2018, 13(4):149-160. CHOULER J, MONTI M D, MORGAN W J, et al. A photosynthetic toxicity biosensor for water[J]. Electrochimica Acta, 2019, 309(6):392-401. 蔡紫鹏, 李莹, 冯萃敏, 等. 水杨梅对铜绿微囊藻和斜生栅藻的抑制作用[J]. 环境工程, 2018, 36(9):41-45. HU Y, CHEN X J, YANG K, et al. Distinct toxicity of silver nanoparticles and silver nitrate to Daphnia magna in M4 medium and surface water[J]. Science of the Total Environment, 2018, 618(3):838-846. BLEWETT T A, DELOMPRÉ P L M, GLOVER C N, et al. Physical immobility as a sensitive indicator of hydraulic fracturing fluid toxicity towards Daphnia magna[J]. Science of the Total Environment, 2018, 635(4):639-643. 金孝伟, 李哲煜, 徐翩翩, 等. 基于发光细菌的微流控型生物传感器研究进展[J]. 分析化学, 2019, 47(2):181-190. MA X Y, WANG X C, NGO H H, et al. Bioassay based luminescent bacteria:interferences, improvements, and applications[J]. Science of the Total Environment, 2014, 468/469(1):1-11. WASITO H, FATONI A, HERMAWAN D, et al. Immobilized bacterial biosensor for rapid and effective monitoring of acute toxicity in water[J]. Ecotoxicology and Environmental Safety, 2019, 170(4):205-209. ZHANG Y, REN T T, HE J H, et al. Acute heavy metal toxicity test based on bacteria-hydrogel[J]. Colloids and Surfaces A:Physicochemical and Engineering Aspects, 2019, 563(12):318-323. ACAR V, ÍNANAN B E, ZEMHERI F, et al. Acute exposure to boron in Nile tilapia (Oreochromis niloticus):median-lethal concentration (LC50), blood parameters, DNA fragmentation of blood and sperm cells[J]. Chemosphere, 2018, 213(9):345-350. GUO D L, MA J, LI R, et al. Genotoxicity effect of nitrobenzene on soybean (Glycine max) root tip cells[J]. Journal of Hazardous Materials, 2010, 178(1/2/3):1030-1034. HE WEI, XIA Y Q, CAO P H, et al. Curcuminoid WZ35 synergize with cisplatin by inducing ROS production and inhibiting TrxR1 activity in gastric cancer cells[J]. Journal of Experimental & Climical Cancer Research, 2019,38(1):1-11. 陈建华, 谢艳颖, 陈世红, 等. 茶多酚对壬基酚所致斑马鱼急性死亡和遗传损伤的保护作用[J]. 环境污染与防治, 2018, 40(10):1126-1131. KIM J W, CHANG K H, ISOBE T, et al. Acute toxicity of benzotriazole ultraviolet stabilizers on freshwater crustacean (Daphnia pulex)[J]. The Journal of Toxicological Sciences, 2011, 36(2):247-251. LARI E, GAUTHIER P, MOHADDES E, et al. Interactive toxicity of Ni, Zn, Cu, and Cd on Daphnia magna at lethal and sub-lethal concentrations[J]. Journal of Hazardous Materials, 2017, 334(3):21-28. Colla N L, BottÉ S E, Marcovecchio J E. Mercury cycling and bioaccumulation in a changing coastal system:from water to aquatic organisms[J]. Marine Pollution Bulletin, 2019, 140(1):40-50. BABIĆ S, BARIŠIĆ J, STIPANIČEV D, et al. Assessment of river sediment toxicity:combining empirical zebrafish embryotoxicity testing with in silico toxicity characterization[J]. Science of the Total Environment, 2018, 643(6):435-450. GAUR H, BHARGAVA A. Glyphosate induces toxicity and modulates calcium and NO signaling in zebrafish embryos[J]. Biochemical and Biophysical Research Communications, 2019, 513(4):1070-1075. JI C Y, YAN L, CHEN Y C, et al. Evaluation of the developmental toxicity of 2,7-dibromocarbazole to zebrafish based on transcriptomics assay[J]. Journal of Hazardous Materials, 2019, 368(4):514-522. 倪芳, 周斯芸, 张瑛, 等. 不同浓度的五氯酚对斑马鱼运动行为的影响[J]. 生态毒理学报, 2013, 8(5):763-771. ROUNTOS K J, KIM J J, HATTENRATH-LEHMANN T K, et al. Effects of the harmful algae, Alexandrium catenella and Dinophysis acuminata, on the survival, growth, and swimming activity of early life stages of forage fish[J]. Marine Environmental Research, 2019, 148(4):46-56. CAPRIELLO T, GRIMALDI M C, COFONE R, et al. Effects of aluminium and cadmium on hatching and swimming ability in developing zebrafish[J]. Chemosphere, 2019, 222(3):243-249. 周斯芸, 张瑛, 魏倡, 等. 四溴双酚A对斑马鱼游动行为的毒性效应研究[J]. 安全与环境学报, 2016, 16(1):387-391. 高静思, 朱佳, 董文艺. 光照对我国常见藻类的影响机制及其应用[J]. 环境工程, 2019,37(5):111-116. 郑凯, 马晓妍, 郝丽伟, 等. 基于叶绿素荧光成像技术的藻毒性检测法的建立及在环境监测中的应用[J]. 环境科学学报, 2019, 39(3):768-773. CHEN Y E, MAO H T, MA J, et al. Biomonitoring chromium Ⅲ or Ⅵ soluble pollution by moss chlorophyll fluorescence[J]. Chemosphere, 2018, 194(12):220-228. ZHANG Y, LIU G J. Effects of cesium accumulation on chlorophyll content and fluorescence of Brassica juncea L.[J]. Journal of Environmental Radioactivity, 2018, 195(12):26-32. BRODL E, WINKLER A, MACHEROUX P. Molecular mechanisms of bacterial bioluminescence[J]. Computational and Structural Biotechnology Journal, 2018, 16:551-564. YE Z F, ZHAO Q L, ZHANG M H, et al. Acute toxicity evaluation of explosive wastewater by bacterial bioluminescence assays using a freshwater luminescent bacterium, Vibrio qinghaiensis sp. Nov[J]. Journal of Hazardous Materials, 2011, 186(2/3):1351-1354. WANG Y, YANG X H, WANG J Y, et al. A DFT-based toxicity QSAR study of aromatic hydrocarbons to Vibrio fischeri:consideration of aqueous freely dissolved concentration[J]. Journal of Hazardous Materials, 2016, 308(1):149-156. 鹿钦礼, 李亮, 刘金亮, 等. 微生物燃料电池的应用研究进展[J].环境工程,2019,37(8):95-100. TATINCLAUX M, GREGOIRE K, LEININGER A, et al. Electricity generation from wastewater using a floating air cathode microbial fuel cell[J]. Water-Energy Nexus, 2018, 1(2):97-103. LOUKANOV A, ANGELOV A, TAKAHASHI Y, et al. Carbon nanodots chelated with metal ions as efficient electrocatalysts for enhancing performance of microbial fuel cell based on sulfate reducing bacteria[J]. Colloids and Surfaces A:Physicochemical and Engineering Aspects, 2019, 574(4):52-61. NGUYEN D T, TAGUCHI K. A disposable water-activated paper-based MFC using dry E.coli biofilm[J]. Biochemical Engineering Journal, 2019, 143:161-168. KIM M, YOUN S M, SHIN S H, et al. Practical field application of a novel BOD monitoring system[J]. Journal of Environmental Monitoring, 2003, 5(4):640-643. YU D B, BAI L, ZHAI J F, et al. Toxicity detection in water containing heavy metal ions with a self-powered microbial fuel cell-based biosensor[J]. Talanta, 2017, 168(6):210-216. DU F Z, XIE B Z, DONG W B, et al. Continuous flowing membraneless microbial fuel cells with separated electrode chambers[J]. Bioresource Technology, 2011, 102(19):8914-8920. FUJIMOTO H, WAKABAYASHI M, YAMASHIRO H, et al. Whole-cell arsenite biosensor using photosynthetic bacterium Rhodovulum sulfidophilum[J]. Applied Microbiology and Biotechnology, 2006, 73(2):332-338. MAEDA I, YAMASHIRO H, YOSHIOKA D, et al. Colorimetric dimethyl sulfide sensor using Rhodovulum sulfidophilumcells based on intrinsic pigment conversion by CrtA[J]. Applied Microbiology & Biotechnology, 2006, 70(4):397-402. 吴立冬, 刘玲, 李丹, 等. 基于亚甲基蓝的水体急性毒性快速检测方法研究[J]. 分析化学, 2016, 44(9):1354-1358. NAKAMURA T, NAGURO I, ICHIJO H. Iron homeostasis and iron-regulated ROS in cell death, senescence and human diseases[J]. Biochimica et Biophysica Acta. General Subjects, 2019, 1863(9):1398-1409. 姜浩瀚, 吕留庄, 景志行, 等. 野生笃斯越桔总花青素对SPCA-1细胞活力抑制及机理[J]. 食品与生物技术学报, 2019, 38(6):102-108. Liman R, Acikbas Y, CiǴerci Í H. Cytotoxicity and genotoxicity of cerium oxide micro and nanoparticles by Allium and Comet tests[J]. Ecotoxicology and Environmental Safety, 2019, 168(1):408-414. ZHANG Z S, WANG X M, LI J F, et al. Inhibitory effects of Enteromorpha linza polysaccharide on micronucleus of Allium sativum root cells[J]. International Journal of Biological Macromolecules, 2016, 87(6):252-255. WU L H, YI H L, YI M. Assessment of arsenic toxicity using Allium/Vicia root tip micronucleus assays[J]. Journal of Hazardous Materials, 2010, 176(1/2/3):952-956. MERLY L, LANGE L, MEŸER M, et al. Blood plasma levels of heavy metals and trace elements in white sharks (Carcharodon carcharias) and potential health consequences[J]. Marine Pollution Bulletin, 2019, 142:85-92. DUAN L, ZHANG C H, GU W, et al. Sub-chronic toxicity of defoamer used in seawater desalination[J]. Biomedical and Environmental Sciences:BES, 2019, 32(5):334-344. LATIRE T, PABIC C L, MOTTIN E, et al. Responses of primary cultured haemocytes from the marine gastropod Haliotis tuberculata under 10-day exposure to cadmium chloride[J]. Aquatic Toxicology, 2012, 109(3):213-221. MATOZZO V, BERTIN V, BATTISTARA M, et al. Does the antibiotic amoxicillin affect haemocyte parameters in non-target aquatic invertebrates? The clam Ruditapes philippinarum and the mussel Mytilus galloprovincialis as model organisms[J]. Marine Environmental Research, 2016, 119(8):51-58. XIAN J A, WANG A L, MIAO Y T, et al. Flow cytometric analysis of in vitro cytotoxicity of cadmium in haemocytes from the tiger shrimp, Penaeus monodon[J]. Bulletin of Environmental Contamination and Toxicology, 2012, 90(1):46-50. 王法琦, 刘薇, 金一和, 等. 胚胎期及哺乳期全氟辛烷磺酸盐(PFOS)暴露对大鼠长时程突触可塑性影响的miRNA组学研究[J].生态毒理学报, 2012, 7(5):491-500. 薛银刚, 刘菲, 江晓栋, 等. 太湖不同湖区冬季沉积物细菌群落多样性[J].中国环境科学, 2018, 38(2):719-728.
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