群体感应信号分子AHLs强化厌氧氨氧化过程综述

刘长远; 韩蕊; 衣隆强; 雷佳慧; 张翠雅; 吴英海

doi:10.13205/j.hjgc.202308032

群体感应信号分子AHLs强化厌氧氨氧化过程综述

doi: 10.13205/j.hjgc.202308032

1. 大连海洋大学海洋与土木工程学院, 辽宁大连 116023;
2. 设施渔业教育部重点实验室(大连海洋大学), 辽宁大连 116023;
3. 湖南大学环境科学与工程学院, 长沙 410082

基金项目:

国家重点研发计划项目(2019YFD0900501)

大连市支持高层次人才创新创业项目(2020RQ111)

辽宁省科技计划项目(2021JH2/10200012)

设施渔业教育部重点实验室开放课题项目(202211)

国家自然科学基金项目(32273186)

详细信息

作者简介:
刘长远(1999-),男,硕士研究生,主要研究方向为水污染控制技术。1312839526@qq.com

通讯作者:
吴英海(1979-),男,博士,副教授,主要研究方向为微生物集聚与调控。wuyinghai@dlou.edu.cn

计量
- 文章访问数: 161
- HTML全文浏览量: 17
- PDF下载量: 3
- 被引次数: 0
出版历程
- 收稿日期: 2022-08-14
- 网络出版日期: 2023-11-15

REVIEW ON ENHANCEMENT OF ANAMMOX PROCESS BY QUORUM SENSING SIGNAL MOLECULES AHLs

1. College of Marine and Civil Engineering, Dalian Ocean University, Dalian 116023, China;
2. Key Laboratory of Environment Controlled Aquaculture (Dalian Ocean University), Ministry of Education, Dalian 116023, China;
3. College of Environmental Science and Engineering, Hunan University, Changsha 410082, China

摘要

摘要: N-酰基高丝氨酸内酯(N-acyl homoserine lactones, AHLs)介导的群体感应(quorum sensing, QS)在细菌中广泛存在,在厌氧氨氧化(Anammox)过程中起着关键作用。近年来对AHLs介导的QS系统如何促进Anammox的研究逐渐增多,研究热点关注外源AHLs如何缩短Anammox系统启动时间,以及提高生物量、功能微生物丰度和活性等方面。为此,归纳了外源AHLs强化Anammox的机制,以及三磷酸腺苷、氮去除相关酶和相关基因在该过程中的关键作用,总结了AHLs信号分子结构差异和特性对Anammox系统脱氮性能的影响,评述了外源AHLs的添加浓度、添加时间和时效性对Anammox过程的促进效果,以及不同环境因素对该过程脱氮的影响,提出了现阶段AHLs强化Anammox过程研究中存在的主要问题及未来的研究方向。
- 厌氧氨氧化 /
- 群体感应 /
- 脱氮 /
- 信号分子 /
- 胞外聚合物
Abstract: Anaerobic ammonia oxidation (Anammox) is a promising process for wastewater treatment. N-acyl homoserine lactones (AHLs) play a key role in the Anammox process. In recent years, studies on how the AHLs-mediated quorum sensing (QS) system contributes to Anammox are increasing, with a focus on how exogenous AHLs shorten the initiation time of the Anammox system and increase biomass, functional microbial abundance and activity. To this end, the mechanisms by which exogenous AHLs enhance Anammox and the key roles played by adenosine triphosphate (ATP), nitrogen removal-related enzymes and associated genes in the process are summarized, the effects of structural differences and properties of AHLs signalling molecules on the denitrification performance of the Anammox system, the effects of the addition concentration, addition time and varying availability of exogenous AHLs on the promotion of the Anammox process, as well as the effects of different environmental factors on the denitrification process are reviewed. The main problems in the current research on the enhancement of the Anammox process by AHLs are presented, and future research directions are pointed out.
- Anammox /
- quorum sensing /
- denitrification /
- signal molecules /
- extracellular polymers

HTML全文

参考文献(54)

[1]	MADEIRA C L,ARAÚJO J C D.Inhibition of anammox activity by municipal and industrial wastewater pollutants:a review[J].Science of the Total Environment,2021,799(10):149449.
[2]	ZHU Z B,ZHANG Y L,LI J,et al.Insight into quorum sensing and microbial community of an anammox consortium in response to salt stress:from “Candaditus Brocadia” to “Candaditus Scalindua”[J].Science of the Total Environment,2021,796:148979.
[3]	LIU L J,XU S H,WANG F,et al.Effect of exogenous N-acyl-homoserine lactones on the anammox process at 15 ℃:nitrogen removal performance,gene expression and metagenomics analysis[J].Bioresource Technology,2021b,341:125760.
[4]	ZHANG Q,FAN N S,FU J J,et al.Role and application of quorum sensing in anaerobic ammonium oxidation (anammox) process:a review[J].Critical Reviews in Environmental Science and Technology,2020,51(6):626-648.
[5]	ZHAO Z C,XIE G J,LIU B F,et al.A review of quorum sensing improving partial nitritation-anammox process:functions,mechanisms and prospects[J].Science of the Total Environment,2021,765:142703.
[6]	LIU L J,JI M,WANG F,et al.N-acyl-l-homoserine lactones release and microbial community changes in response to operation temperature in an anammox biofilm reactor[J].Chemosphere,2021,262:127602.
[7]	HUANG D Q,FU J J,LI Z Y,et al.Inhibition of wastewater pollutants on the anammox process:a review[J].Science of the Total Environment,2022,803:150009.
[8]	ZHANG J,ZHANG Y C,WANG X J,et al.Effects of substrate shock on release of AHL signals in ANAMMOX granules and properties of granules[J].Environmental Science:Water Research & Technology,2019,5(4):756-768.
[9]	FENG Z L,GU M Q,SUN Y P,et al.Potential microbial functions and quorum sensing systems in partial nitritation and anammox processes[J].Water Environment Research,2021,93(9):1562-1575.
[10]	TAHA M O,AL-BAKRI A G,ZALLOUM W A.Discovery of potent inhibitors of pseudomonal quorum sensing via pharmacophore modeling and in silico screening[J].Bioorganic & Medicinal Chemistry Letters,2006,16(22):5902-5906.
[11]	TRIPATHI S,CHANDRA R,PURCHASE D,et al.Quorum sensing-a promising tool for degradation of industrial waste containing persistent organic pollutants[J].Environmental Pollution,2022,292(B):118342.
[12]	PAPENFORT K,BASSLER B L.Quorum sensing signal-response systems in Gram-negative bacteria[J].Nature Reviews Microbiology,2016,14(9):576-588.
[13]	FUQUA W C,WINANS S C,GREENBERG E P.Quorum sensing in bacteria:the LuxR-LuxI family of cell density-responsive transcriptional regulators[J].Journal of Bacteriology,1994,176(2):269-275.
[14]	FUQUA C,PARSEK M R,GREENBERG E P.Regulation of gene expression by cell-to-cell communication:acyl-homoserine lactone quorum sensing[J].Annual Review of Genetics,2001,35(1):439-468.
[15]	RUHAL R,KATARIA R.Biofilm patterns in gram-positive and gram-negative bacteria[J].Microbiological Research,2021,251:126829.
[16]	CHONG G,KIMYON O,RICE S A,et al.The presence and role of bacterial quorum sensing in activated sludge:quorum sensing in activated sludge[J].Microbial Biotechnology,2012,5(5):621-633.
[17]	LIU L L,ZENG X Y,ZHENG J,et al.AHL-mediated quorum sensing to regulate bacterial substance and energy metabolism:a review[J].Microbiological Research,2022,262:127102.
[18]	MA M J,CAO Q F,MABRUK A,et al.Promotion of nitrogen removal and microbial enrichment on anammox by exogenous substance addition:A critical review[J].Journal of Water Process Engineering,2022,49:103096.
[19]	ZHAO R,ZHANG H M,ZHANG F,et al.Fast start-up anammox process using Acyl-homoserine lactones (AHLs) containing supernatant[J].Journal of Environmental Sciences,2018,65:127-132.
[20]	WU P,CHEN J J,GARLAPATI V K,et al.Novel insights into Anammox-based processes:a critical review[J].Chemical Engineering Journal,2022,444:136534.
[21]	WANG W Y,WANG R,ABBAS G,et al.Aggregation enhances the activity and growth rate of anammox bacteria and its mechanisms[J].Chemosphere,2022,291:132907.
[22]	VANDANA,DAS S.Structural and mechanical characterization of biofilm-associated bacterial polymer in the emulsification of petroleum hydrocarbon[J].3 Biotech,2021,11(5):239.
[23]	SUN Y P,GUAN Y T,WANG D,et al.Potential roles of acyl homoserine lactone based quorum sensing in sequencing batch nitrifying biofilm reactors with or without the addition of organic carbon[J].Bioresource Technology,2018,259:136-145.
[24]	CHEN H,LI A,CUI C W,et al.AHL-mediated quorum sensing regulates the variations of microbial community and sludge properties of aerobic granular sludge under low organic loading[J].Environment International,2019,130:104946.
[25]	JI Y T,YU H T,CAO R J,et al.Promoting the granulation process of aerobic sludge via a sustainable strategy of effluent reflux in view of AHLs-mediated quorum sensing[J].Journal of Environmental Management,2022,303:114091.
[26]	HAN H,LI J,ZHANG J,et al.Enhancing the treatment performance of partial denitrification/Anammox process at high nitrogen load:effects of immobilized strain HFQ8_C/N on the sludge characteristics[J].Bioresource Technology,2021,341:125870.
[27]	TANG X,GUO Y Z,WU S S,et al.Metabolomics uncovers the regulatory pathway of acyl-homoserine lactones based quorum sensing in anammox consortia[J].Environmental Science & Technology,2018,52(4):2206-2216.
[28]	ZHANG Z M,CAO R J,JIN L N,et al.The regulation of N-acyl-homoserine lactones (AHLs)-based quorum sensing on EPS secretion via ATP synthetic for the stability of aerobic granular sludge[J].Science of the Total Environment,2019,673:83-91.
[29]	LIU Y M,GUO J B,LIAN J,et al.Effects of extracellular polymeric substances (EPS) and N-acyl-L-homoserine lactones (AHLs) on the activity of anammox biomass[J].International Biodeterioration & Biodegradation,2018,129:141-147.
[30]	TANG X,LIU S T,ZHANG Z T,et al.Identification of the release and effects of AHLs in anammox culture for bacteria communication[J].Chemical Engineering Journal,2015,273:184-191.
[31]	陈舒涵,李安婕,王越兴,等.厌氧氨氧化污泥群体感应信号分子检测及影响研究[J].环境科学,2017,38(3):1137-1143.
[32]	GAO J,DUAN Y,LIU Y,et al.Long- and short-chain AHLs affect AOA and AOB microbial community composition and ammonia oxidation rate in activated sludge[J].Journal of Environmental Sciences,2019,78:53-62.
[33]	ZHAO R,ZHANG H M,ZOU X,et al.Effects of inhibiting acylated homoserine lactones (AHLs) on anammox activity and stability of granules[J].Current Microbiology,2016,73(1):108-114.
[34]	ZHU Z Q,YANG Y,FANG A R,et al.Quorum sensing systems regulate heterotrophic nitrification-aerobic denitrification by changing the activity of nitrogen-cycling enzymes[J].Environmental Science and Ecotechnology,2020,2:100026.
[35]	CHENG Y,ZHANG Y,SHEN Q X,et al.Effects of exogenous short-chain N-acyl homoserine lactone on denitrifying process of Paracoccus denitrificans[J].Journal of Environmental Sciences,2017,54:33-39.
[36]	TANG X,GUO Y Z,ZHU T T,et al.Identification of quorum sensing signal AHLs synthases in Candidatus Jettenia caeni and their roles in anammox activity[J].Chemosphere,2019,225:608-617.
[37]	FENG Z L,WU Y H,SHI Y H,et al.Successful startup of one-stage partial nitritation and anammox system through cascade oxygen supply and potential ecological network analysis[J].Science of the Total Environment,2019,696:134065.
[38]	FUQUA C,PETER GREENBERG E.Listening in on bacteria:acyl-homoserine lactone signalling[J].Nature Reviews Molecular Cell Biology,2002,3(9):685-695.
[39]	CHURCHILL M E A,CHEN L L.Structural basis of acyl-homoserine lactone-dependent signaling[J].Chemical Reviews,2011,111:68-85.
[40]	DECHO A W,FREY R L,FERRY J L.Chemical challenges to bacterial AHL signaling in the environment[J].Chemical Reviews,2011,111(1):86-99.
[41]	ZHANG J,ZHANG Y Z,ZHAO B H,et al.Effects of pH on AHL signal release and properties of ANAMMOX granules with different biomass densities[J].Environmental Science:Water Research & Technology,2019,5(10):1723-1735.
[42]	LIU L J,JI M,WANG F,et al.Insight into the short-term effect of fulvic acid on nitrogen removal performance and N-acylated-L-homoserine lactones (AHLs) release in the anammox system[J].Science of the Total Environment,2020,704:135285.
[43]	LI A J,HOU B L,LI M X.Cell adhesion,ammonia removal and granulation of autotrophic nitrifying sludge facilitated by N-acyl-homoserine lactones[J].Bioresource Technology,2015,196:550-558.
[44]	DECHO A W,SEAN NORMAN R,VISSCHER P T.Quorum sensing in natural environments:emerging views from microbial mats[J].Trends in Microbiology,2010,18:73-80.
[45]	WANG J F,LIU Q J,DONG D Y,et al.AHLs-mediated quorum sensing threshold and its response towards initial adhesion of wastewater biofilms[J].Water Research,2021,194:116925.
[46]	TAIT K,JOINT I,DAYKIN M,et al.Disruption of quorum sensing in seawater abolishes attraction of zoospores of the green alga Ulva to bacterial biofilms[J].Environmental Microbiology,2005,7(2):229-240.
[47]	ZHANG J,LI J,ZHAO B H,et al.Long-term effects of N-acyl-homoserine lactone-based quorum sensing on the characteristics of ANAMMOX granules in high-loaded reactors[J].Chemosphere,2019a,218:632-642.
[48]	CHOI D,SIM B O,JUNG J Y.Activation of N-acyl-homoserine lactone-mediated quorum sensing system improves long-term preservation of anammox microorganisms by vacuum lyophilization[J].Chemosphere,2022,301:134743.
[49]	SEET Q,ZHANG L H.Anti-activator QslA defines the quorum sensing threshold and response in Pseudomonas aeruginosa:quorum sensing anti-activator QslA[J].Molecular Microbiology,2011,80(4):951-965.
[50]	WEI C,SONG L J,ZHAO Y R,et al.The experimental research on the start-up and stable operation phase of ANAMMOX system[J].Applied Mechanics and Materials,2015,744/745/746:2407-2416.
[51]	CHO S,KAMBEY C,NGUYEN V.Performance of anammox processes for wastewater treatment:a critical review on effects of operational conditions and environmental stresses[J].Water,2019,12(1):20.
[52]	YAN H,LI J Z,MENG J,et al.Insight into the effect of N-acyl-homoserine lactones-mediated quorum sensing on the microbial social behaviors in a UASB with the regulation of alkalinity[J].Science of the Total Environment,2021,800:149413.
[53]	DECHO A W,VISSCHER P T,FERRY J L,et al.Autoinducers extracted from microbial mats reveal a surprising diversity of N-acylhomoserine lactones (AHLs) and abundance changes that may relate to diel pH[J].Environmental Microbiology,2009,11:409-420.
[54]	RANA S,BHAWAL S,KUMARI A,et al.pH-dependent inhibition of AHL-mediated quorum sensing by cell-free supernatant of lactic acid bacteria in Pseudomonas aeruginosa PAO1[J].Microbial Pathogenesis,2020,142:104105.