参数σ2(k·ECx)与多元混合物联合作用的关系研究

王 娜; 杨鑫悦; 蔡文涛; 孙嘉靖; 马晓妍; 张豫姣

doi:10.13205/j.hjgc.202403007

参数σ²_{(k·EC_x)}与多元混合物联合作用的关系研究

doi: 10.13205/j.hjgc.202403007

1. 西安科技大学建筑与土木工程学院, 西安 710054;
2. 东营市生态环境局广饶县分局, 山东东营 257000;
3. 西安建筑科技大学环境与市政工程学院, 西安 710055

基金项目:

国家自然科学基金项目(51708447)

详细信息

作者简介:
王娜：王娜(1981-),女,博士,讲师,主要研究方向为水体生物毒性评价。wangna811221@126.com

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出版历程
- 收稿日期: 2023-04-11
- 网络出版日期: 2024-05-31

RELATIONSHIP BETWEEN PARAMETER σ²_{(k·EC_x) AND INTERACTION OF MULTI-COMPONENT MIXTURES}

1. School of Architecture and Civil Engineering, Xi'an University of Science and Technology, Xi'an 710054, China;
2. Guangrao County Branch, Dongying Ecological and Environmental Bureau, Dongying 257000, China;
3. School of Environmental and Municipal Engineering, Xi'an University of Architecture and Technology, Xi'an 710055, China

摘要

摘要: 表征多元混合物各组分浓度效应曲线(CRC)形态差异的参数σ²_{(k·EC_x)可以预测多元混合物的联合毒性,进一步探索σ²_{(k·EC_x)与多元混合物联合作用强度和方式的关系。选取11种环境污染物,按照物质CRC的参数k·EC_x的数值分为D组(相异体系)和S组(相似体系),设计18组多元混合物,借助独立作用模型(IA)和效应残差比(ERR_x)模型评价混合物的联合作用。结果表明:D组混合体系易发生联合作用方式的转变;S组混合体系联合作用方式保持不变。D组中σ²_{(k·EC_x)}较大的混合物不易发生联合作用方式的转变。D组混合物整体联合作用强度大于S组,各混合体系内联合作用强度与σ²_{(k·EC_x)}正相关。该研究揭示了参数σ²_{(k·EC_x)与多元混合物联合作用的关系,实现了从几何角度对多元混合物联合作用的预判,为环境风险评价提供一定的理论支持。}}}
- σ²_{(k·EC_x)} /
- IA /
- 费氏弧菌 /
- 急性毒性 /
- 联合作用
Abstract: Previous studies have found that the parameter k·EC_x can characterize the shape of the concentration-reaction curves (CRCs), and its derived parameter σ²_{(k·EC_x)} (the variance of k·EC_x for each component) can predict the combined toxicity of multi-component mixtures. This study further explored the relationship between σ²_{(k·EC_x}) and the strength and mode of joint action. Eleven environmental pollutants were divided into group D (different system) and group S (similar system) according to the value of parameter k·EC_x. A total of 18 mixtures (11 in group D, and 7 in group S) were designed. The joint action of mixtures was evaluated by independent action model (IA) and effect residual ratio (ERR_x) model. The mixed systems with different parameters k·EC_x (group D in this paper) were prone to change the mode of joint action. The mixed systems with similar k·EC_x of each component (group S in this paper) kept the mode of interaction unchanged. In the group D, the mode of interaction of mixtures with a larger σ²_{(k·EC_x)} was not easy to change. The strength of the joint action of group D was greater than that of group S overall. The strength of the interaction in every mixed system was positively correlated with the σ²_{(k·EC_x)}. This study revealed the relationship between the σ²_{(k·EC_x)} and the joint action of multiple mixtures, and achieved the prejudgement of the joint action of multiple mixtures from a geometric perspective, which can provide certain theoretical support for the environmental risk assessment.
- σ²_{(k·EC_x)} /
- IA /
- aliivibrio fischeri /
- acute toxicity /
- joint action

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参考文献(26)

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