典型抗生素对污泥厌氧消化效能的影响及调控策略研究进展

金翝启; 姜荣杰; 王子睿; 李璐杨; 罗景阳

doi:10.13205/j.hjgc.202407005

典型抗生素对污泥厌氧消化效能的影响及调控策略研究进展

doi: 10.13205/j.hjgc.202407005

金翝启^1,2,
姜荣杰^1,2,
王子睿^1,2,
李璐杨^1,2,
罗景阳^1,2, ,

1. 河海大学浅水湖泊综合治理与资源开发教育部重点实验室, 南京 210098;
2. 河海大学环境学院, 南京 210098

基金项目:

国家自然科学基金项目(52070069)

国家级大学生创新创业训练计划(202310294003Z)

详细信息

作者简介:
金翝启(2003-),男,本科生,主要研究方向为有毒有害污染物控制理论与技术及有机废物的资源化利用。2114040116@hhu.edu.cn

通讯作者:
罗景阳(1989-),男,工学博士,教授,博士生导师,主要研究方向为有毒有害污染物控制理论与技术及有机废物的资源化利用。luojy2016@hhu.edu.cn

计量
- 文章访问数: 12
- HTML全文浏览量: 7
- PDF下载量: 0
- 被引次数: 0
出版历程
- 收稿日期: 2024-04-23
- 网络出版日期: 2024-12-02

RESEARCH PROGRESS ON IMPACT AND REGULATION STRATEGIES OF TYPICAL ANTIBIOTICS ON ANAEROBIC DIGESTION EFFICIENCY OF SLUDGE: A REVIEW

JIN Hongqi^1,2,
JIANG Rongjie^1,2,
WANG Zirui^1,2,
LI Luyang^1,2,
LUO Jingyang^{1,2
, ,}

1. Key Laboratory of Integrated Regulation and Resource Development on Shallow Lakes of the Ministry of Education, Hohai University, Nanjing 210098, China;
2. College of Environment, Hohai University, Nanjing 210098, China

摘要

摘要: 厌氧消化是实现污泥等废弃物资源化利用和无害化处理的有效手段。近年来,抗生素被广泛滥用,并不可避免地对污泥厌氧消化体系产生潜在影响。综合探讨了不同抗生素在不同环境条件下(温度、浓度、底物、暴露方式、复合存在等)对污泥厌氧消化效能的影响。结果表明,不同抗生素对污泥厌氧消化的影响可归结为抑制、促进和无影响等,其中抑制作用更为普遍。进一步分析发现,抗生素主要通过破坏功能菌群结构、改变代谢途径(如酶活性、胞外聚合物分泌)、影响群体感应机制等方式影响系统效能。然而,通过采用物理处理(如水热、超声等)、化学处理(如高级氧化技术、臭氧、电化学等)、生物处理(如外源添加生物酶、外源添加材料加速电子传递等)、联合处理(碱热、超声/臭氧等)等预处理手段可有效削减系统中抗生素的不利影响,提升厌氧消化效能。最后,从预处理手段的优化、抗生素迁移对生态系统潜在影响等角度进行了展望,可为提升厌氧消化效能提供参考。
- 污泥 /
- 厌氧消化 /
- 抗生素 /
- 代谢途径 /
- 削减策略
Abstract: Anaerobic digestion is one of the most effective and eco-friendly technologies for resource utilization and harmless disposal of organic wastes. In recent years, antibiotics have been widely misused and enriched into sludge, which inevitably has a potential impact on the anaerobic digestion system of sludge. This study comprehensively investigated the effects of different antibiotics on the efficacy of anaerobic digestion of sludge under various environmental conditions (temperature, concentration, substrate, exposure mode, coexistence, etc.). The results showed that antibiotics were generally inhibitory and a few tended to promote and restore. The reason for this discrepancy could be attributed to the variability in the effects of antibiotics on cell structure disruption (e.g., cell wall structure), metabolic pathways (e.g., enzyme activity, extracellular polymer secretion), and adaptive mechanisms (quorum sensing systems). However, the adverse effects of antibiotics in the system could be effectively reduced, and anaerobic digestion efficacy could be enhanced by adopting physical (such as hydrothermal, ultrasound, etc.), chemical (such as advanced oxidation technologies, ozone, electrochemistry, etc.), biological (such as the addition of exogenous bioenzymes, materials to accelerate electron transfer, etc.), and combined (such as alkali heat, ultrasound-ozone, etc.) pretreatment methods. Finally, prospects for the optimization of pretreatment methods and the potential impacts of antibiotic migration on ecosystems were discussed, which could provide references for enhancing the efficacy of anaerobic digestion.
- sludge /
- anaerobic digestion /
- antibiotics /
- metabolic pathway /
- reduction strategy

HTML全文

参考文献(64)

[1]	ZHANG J, YANG Y, SUN C, et al. Sample preparation and instrumental detection methods for tetracycline antibiotics[J]. International Journal of Environmental Analytical Chemistry, 2023, 1-30.
[2]	ZHOU H, CAO Z, ZHANG M, et al. Zero-valent iron enhanced in-situ advanced anaerobic digestion for the removal of antibiotics and antibiotic resistance genes in sewage sludge[J]. Science of the Total Environment 2021, 754: 142077.
[3]	牟霄, 张崇淼, 李永强, 等. 典型抗生素在城市污水处理厂各单元出水中的分布及受纳水体生态风险[J]. 生态毒理学报, 2023, 18(3): 366-375.
[4]	张翔宇, 李茹莹, 季民. 污水生物处理中抗生素的去除机制及影响因素[J]. 环境科学, 2018, 39(11): 5276-5288.
[5]	董亚荣, 张桂芹, 伊丽丽, 等. 氟喹诺酮类抗生素在污水处理厂中去除途径研究[J]. 河北环境工程学院学报, 2023, 33(6): 77-81.
[6]	黄小丁. 克拉霉素对污泥厌氧消化的影响及控制研究[D]. 长沙:湖南大学, 2020.
[7]	HUANG X, LIU X, CHEN F, et al. Clarithromycin affect methane production from anaerobic digestion of waste activated sludge[J]. Journal of Cleaner Production, 2020, 255: 120321.
[8]	ZENG S, SUN J, CHEN Z, et al. The impact and fate of clarithromycin in anaerobic digestion of waste activated sludge for biogas production[J]. Environmental Research, 2021, 195: 110792.
[9]	ZHI S, ZHANG K. Antibiotic residues may stimulate or suppress methane yield and microbial activity during high-solid anaerobic digestion[J]. Chemical Engineering Journal, 2019, 359: 1303-1315.
[10]	YUN H, LIANG B, HE Z, et al. Insights into methanogenesis of mesophilic-psychrophilic varied anaerobic digestion of municipal sludge with antibiotic stress[J]. Journal of Environmental Management, 2023, 331: 117278.
[11]	马晶伟, 易可为, 何秋来, 等. 氧氟沙星与聚苯乙烯微塑料复合污染对剩余污泥厌氧消化的影响[J]. 环境工程学报, 2022, 16(7): 2335-2346.
[12]	XIANG Y, XIONG W, YANG Z, et al. Coexistence of microplastics alters the inhibitory effect of antibiotics on sludge anaerobic digestion[J]. Chemical Engineering Journal, 2023, 455: 140754.
[13]	ZENG S, SUN J, LV X, et al. Impacts of norfloxacin on sewage sludge anaerobic digestion: bioenergy generation and potential environmental risks[J]. Results in Engineering, 2023, 20: 101392.
[14]	ZHU K, ZHANG L, WANG X, et al. Inhibition of norfloxacin on anaerobic digestion: focusing on the recoverability and shifted microbial communities[J]. Science of the Total Environment 2021, 752, 141733.
[15]	MA J, SHU L, MITCHELL S M, et al. Effects of different antibiotic operation modes on anaerobic digestion of dairy manure: focus on microbial population dynamics[J]. Journal of Environmental Chemical Engineering, 2021, 9(4): 105521.
[16]	马清佳, 田哲, 员建, 等. 9种抗生素对污泥高温厌氧消化的急性抑制[J]. 环境工程学报, 2018, 12(7): 2084-2093.
[17]	LU X, ZHEN G, LIU Y, et al. Long-term effect of the antibiotic cefalexin on methane production during waste-activated sludge anaerobic digestion[J]. Bioresource Technology, 2014, 169: 644-651.
[18]	RANI J, STABLEIN M J, PATEL K, et al. Monitoring effects of tetracycline and spectinomycin perturbations on biogas production and microbiome dynamics in a batch mesophilic anaerobic digester[J]. BioEnergy Research, 2024, 17(2):1263-1276.
[19]	CHEN H, ZENG X, ZHOU Y, et al. Influence of roxithromycin as antibiotic residue on volatile fatty acids recovery in anaerobic fermentation of waste activated sludge[J]. Journal of Hazardous Materials, 2020, 394: 122570.
[20]	ZHU W, BU F, XU J, et al. Influence of lincomycin on anaerobic digestion: sludge type, biogas generation, methanogenic pathway and resistance mechanism[J]. Bioresource Technology, 2021, 329: 124913.
[21]	LINS P, REITSCHULER C, ILLMER P. Impact of several antibiotics and 2-bromoethanesulfonate on the volatile fatty acid degradation, methanogenesis and community structure during thermophilic anaerobic digestion[J]. Bioresource Technology, 2015, 190: 148-158.
[22]	BENERAGAMA N, LATEEF S A, IWASAKI M, et al. The combined effect of cefazolin and oxytertracycline on biogas production from thermophilic anaerobic digestion of dairy manure[J]. Bioresource Technology, 2013, 133: 23-30.
[23]	WEILAND P. Biogas production: current state and perspectives[J]. Applied Microbiology and Biotechnology, 2010, 85: 849-860.
[24]	LI B, KANG W, LIU H, et al. The antimicrobial activity of Cbf-K16 against MRSA was enhanced by β-lactamantibiotics through cell wall non-integrity[J]. Archives of Pharmacal Research, 2016, 39(7): 978-988.
[25]	陈玉连. 深圳河湾流域表层沉积物中深古菌及产甲烷古菌群落结构的研究[D]. 广东:深圳大学, 2019.
[26]	HILPERT R, WINTER J, HAMMES W, et al. The sensitivity of archaebacteria to antibiotics[J]. Zentralblatt für Bakteriologie Mikrobiologie und Hygiene: I Abt Originale C: Allgemeine, Angewandte und Ökologische Mikrobiologie, 1981, 2(1): 11-20.
[27]	CZATZKOWSKA M, HARNISZ M, KORZENIEWSKA E, et al. The impact of antimicrobials on the efficiency of methane fermentation of sewage sludge, changes in microbial biodiversity and the spread of antibiotic resistance[J]. Journal of Hazardous Materials, 2021(6): 125773.
[28]	XIANG Y P, XIONG W P, XU R, et al. Metagenomic analysis reveals microbial metabolic potentials alterations under antibiotic stress during sludge anaerobic digestion [J]. Journal of Environmental Chemical Engineering, 2023, 11(5). 10.1016/j.cie.2022.108635.
[29]	WANG X, LYU T, DONG R, et al. Revealing the link between evolution of electron transfer capacity of humic acid and key enzyme activities during anaerobic digestion[J]. Journal of Environmental Management, 2022, 301: 113914.
[30]	CETECIOGLU Z, INCE B, ORHON D, et al. Acute inhibitory impact of antimicrobials on acetoclastic methanogenic activity[J]. Bioresource Technology, 2012, 114: 109-116.
[31]	CHEN H, ZENG X, ZHOU Y, et al. Influence of roxithromycin as antibiotic residue on volatile fatty acids recovery in anaerobic fermentation of waste activated sludge[J]. Journal of Hazardous Materials, 2020, 394: 122570.
[32]	YUAN-Da, KONG, QIANG, et al. Pollutant removal and microorganism evolution of activated sludge under ofloxacin selection pressure[J]. Bioresource Technology: Biomass, Bioenergy, Biowastes, Conversion Technologies, Biotransformations, Production Technologies, 2017, 241: 849-856.
[33]	叶超, 陈毅刚. 抗生素对活性污泥系统运行效果及代谢产物的影响:以氧氟沙星为例[J]. 环境科技, 2020, 33(4): 29-33.
[34]	谢淑仪, 陈姗姗, 栾天罡. 电活性微生物胞外聚合物的特征与应用[J]. 微生物学报, 2023, 63(2): 540-552.
[35]	ZHANG J, YUE Z, ZHOU Z, et al. Key microbial clusters and environmental factors affecting the removal of antibiotics in an engineered anaerobic digestion system[J]. Bioresource Technology, 2022, 348: 126770.
[36]	朱艮苗, 杨维青. 群体感应系统对细菌耐药的调控作用[J]. 中国抗生素杂志, 2011, 36(1): 7-10.
[37]	MAEDA T, SABIDI S, SANCHEZ-Torres V, et al. Engineering anaerobic digestion via optimizing microbial community: effects of bactericidal agents, quorum sensing inhibitors, and inorganic materials[J]. Applied Microbiology and Biotechnology, 2021, 105(20): 7607-7618.
[38]	李宵宵.水热预处理强化高含固污泥厌氧消化的研究[D]. 太原:太原理工大学, 2020.
[39]	陈仁杰, 董滨, 戴晓虎.水热技术在污泥无害化处理中的应用及展望[J]. 环境工程, 2023, 41(9): 201-209.
[40]	柳珊, 郭春春, 马艳芳, 等.水热预处理对猪粪厌氧消化系统中磺胺嘧啶降解的影响[J].农业工程学报, 2023, 39(22): 188-198.
[41]	SUN C, LI W, CHEN Z, et al. Responses of antibiotics, antibiotic resistance genes, and mobile genetic elements in sewage sludge to thermal hydrolysis pre-treatment and various anaerobic digestion conditions[J]. Environment International, 2019, 133: 105156.
[42]	HE Y, TIAN Z, YI Q, et al. Impact of oxytetracycline on anaerobic wastewater treatment and mitigation using enhanced hydrolysis pretreatment[J]. Water Research, 2020, 187: 116408.
[43]	LI N, LIU H, XUE Y, et al. Partition and fate analysis of fluoroquinolones in sewage sludge during anaerobic digestion with thermal hydrolysis pretreatment[J]. Science of the Total Environment, 2017, 581/582: 715-721.
[44]	LI X, GUO S, PENG Y, et al. Anaerobic digestion using ultrasound as pretreatment approach: changes in waste activated sludge, anaerobic digestion performances and digestive microbial populations[J]. Biochemical Engineering Journal, 2018, 139: 139-145.
[45]	WU Y, WANG S, LIANG D, et al. Conductive materials in anaerobic digestion: from mechanism to application[J]. Bioresource Technology, 2020, 298: 122403.
[46]	ZHANG X, LI R. Variation of antibiotics in sludge pretreatment and anaerobic digestion processes: degradation and solid-liquid distribution[J]. Bioresource Technology, 2018, 255: 266-272.
[47]	LIU H, WANG X, QIN S, et al. Comprehensive role of thermal combined ultrasonic pre-treatment in sewage sludge disposal[J]. Science of the Total Environment, 2021, 789: 147862.
[48]	ZHANG X, GANG D D, LEI X, et al. Surface-bound hydroxyl radical-dominated degradation of sulfamethoxazole in the amorphous FeOOH/peroxymonosulfate system: the key role of amorphous structure enhancing electron transfer[J]. Environmental Research, 2022, 214: 113964.
[49]	XIE L, ZHU J, XIE J, et al. Underlying the inhibition mechanisms of sulfate and lincomycin on long-term anaerobic digestion: microbial response and antibiotic resistance genes distribution[J]. Science of the Total Environment, 2024, 915: 169837.
[50]	ZGAJNAR Gotvajn A, DERCO J, VRABEL M, et al. Improvement of biotreatability of environmentally persistent antibiotic Tiamulin by O₃ and O₃/H₂O₂ oxidation processes[J]. Environment Technology, 2022, 43(15): 2319-2328.
[51]	BOSEVSKI I, GOTVAJN A Z. The impact of single step ozonation of antibiotics-contaminated waste sludge to biogas production[J]. Chemosphere, 2021, 271: 129527.
[52]	CHANDRASEKHAR K, AMULYA K, MOHAN S V. Solid phase bio-electrofermentation of food waste to harvest value-added products associated with waste remediation[J]. Waste Management, 2015, 45: 57-65.
[53]	XUE W, ZHOU Q, LI F. Bacterial community changes and antibiotic resistance gene quantification in microbial electrolysis cells during long-term sulfamethoxazole treatment[J]. Bioresource Technology, 2019, 294: 122170.
[54]	YAN W, XIAO Y, YAN W, et al. The effect of bioelectrochemical systems on antibiotics removal and antibiotic resistance genes: a review[J]. Chemical Engineering Journal, 2019, 358: 1421-1437.
[55]	HU D, MIN H, WANG H, et al. Performance of an up-flow anaerobic bio-electrochemical system (UBES) for treating sulfamethoxazole (SMX) antibiotic wastewater[J]. Bioresource Technology, 2020, 305: 123070.
[56]	孔峰, 戴雅, 刘阳, 等. 电化学预处理对后续厌氧消化工艺的作用研究[J]. 水处理技术, 2017, 43(2): 6.
[57]	曹正操. 酶促集成原位高级厌氧消化去除抗生素及抗性基因规律研究[D]. 上海:上海理工大学, 2023.
[58]	CHENG D, NGO H H, GUO W, et al. Improving sulfonamide antibiotics removal from swine wastewater by supplying a new pomelo peel derived biochar in an anaerobic membrane bioreactor[J]. Bioresource Technology, 2021, 319: 124160.
[59]	Min ZHANG, Jianhua LI, Yuncai WANG, et al. Impacts of different biochar types on the anaerobic digestion of sewage sludge[J]. RSC Advances, 2019(9): 42375-42386.
[60]	ZHOU H, CAO Z, ZHANG M, et al. Zero-valent iron enhanced in-situ advanced anaerobic digestion for the removal of antibiotics and antibiotic resistance genes in sewage sludge[J]. Science of the Total Environment, 2021, 754: 142077.
[61]	NI Z, ZHOU L, LIN Z, et al. Iron-modified biochar boosts anaerobic digestion of sulfamethoxazole pharmaceutical wastewater: performance and microbial mechanism[J]. Journal of Hazardous Materials, 2023, 452: 131314.
[62]	宋思奇. 碱热预处理-导电介质强化厌氧处理大观霉素菌渣效能与机制[D]. 哈尔滨:哈尔滨工业大学, 2023.
[63]	ZHAO Q, LI M, ZHANG K, et al. Effect of ultrasound irradiation combined with ozone pretreatment on the anaerobic digestion for the biosludge exposed to trace-level levofloxacin: degradation, microbial community and ARGs analysis[J]. Journal of Environmental Management, 2020, 262: 110356.
[64]	CHEN X, TANG R, WANG Y, et al. Effect of ultrasonic and ozone pretreatment on the fate of enteric indicator bacteria and antibiotic resistance genes, and anaerobic digestion of dairy wastewater[J]. Bioresource Technology, 2021, 320: 124356.

施引文献

资源附件(0)

访问统计

点击查看大图

计量

文章访问数: 12
HTML全文浏览量: 7
PDF下载量: 0
被引次数: 0

姓名
邮箱
手机号码
标题
留言内容
验证码

留言板

典型抗生素对污泥厌氧消化效能的影响及调控策略研究进展

doi: 10.13205/j.hjgc.202407005

作者简介:
金翝启(2003-),男,本科生,主要研究方向为有毒有害污染物控制理论与技术及有机废物的资源化利用。2114040116@hhu.edu.cn

通讯作者:
罗景阳(1989-),男,工学博士,教授,博士生导师,主要研究方向为有毒有害污染物控制理论与技术及有机废物的资源化利用。luojy2016@hhu.edu.cn

计量

RESEARCH PROGRESS ON IMPACT AND REGULATION STRATEGIES OF TYPICAL ANTIBIOTICS ON ANAEROBIC DIGESTION EFFICIENCY OF SLUDGE: A REVIEW

计量

目录

期刊在线

作者中心

友情链接

留言板

典型抗生素对污泥厌氧消化效能的影响及调控策略研究进展

doi: 10.13205/j.hjgc.202407005

作者简介: 金翝启(2003-),男,本科生,主要研究方向为有毒有害污染物控制理论与技术及有机废物的资源化利用。2114040116@hhu.edu.cn

通讯作者: 罗景阳(1989-),男,工学博士,教授,博士生导师,主要研究方向为有毒有害污染物控制理论与技术及有机废物的资源化利用。luojy2016@hhu.edu.cn

计量

出版历程

RESEARCH PROGRESS ON IMPACT AND REGULATION STRATEGIES OF TYPICAL ANTIBIOTICS ON ANAEROBIC DIGESTION EFFICIENCY OF SLUDGE: A REVIEW

计量

出版历程

目录

期刊在线

作者中心

友情链接

作者简介:
金翝启(2003-),男,本科生,主要研究方向为有毒有害污染物控制理论与技术及有机废物的资源化利用。2114040116@hhu.edu.cn

通讯作者:
罗景阳(1989-),男,工学博士,教授,博士生导师,主要研究方向为有毒有害污染物控制理论与技术及有机废物的资源化利用。luojy2016@hhu.edu.cn