人工湿地中抗生素的转化风险及其安全控制

陆佳兴; 胡振; 刘华清; 孔强; 崔世璇; 纪明德; 张建

doi:10.13205/j.hjgc.202610009

人工湿地中抗生素的转化风险及其安全控制

doi: 10.13205/j.hjgc.202610009

陆佳兴¹,
胡振²,
刘华清³,
孔强¹,
崔世璇⁴,
纪明德¹,
张建^4, ,

1. 山东师范大学地理与环境学院山东省新污染物风险防控重点实验室, 济南 250014;
2. 山东大学环境科学与工程学院, 山东青岛 266237;
3. 山东科技大学安全与环境工程学院, 山东青岛 266590;
4. 山东师范大学化学化工与材料科学学院, 济南 250014

基金项目:

国家自然科学基金重点项目（52430005）；国家自然科学基金项目（52500223）；山东省自然科学基金重大基础研究项目（ZR2026ZD55）

详细信息

作者简介:
陆佳兴（1997—），男，副教授，主要研究方向为新污染物的环境行为、效应及控制。lujiaxing83@sdnu.edu.cn

通讯作者:
张建（1976—），男，教授，主要研究方向为环境污染物控制与资源化利用。zhangjian@sdnu.edu.cn

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出版历程
- 收稿日期: 2026-08-20
- 网络出版日期: 2026-11-10

Transformation risks of antibiotics in constructed wetlands and safety control strategies

1. Shandong Province Key Laboratory of Emerging Contaminants Risk Prevention and Control, College of Geography and Environment, Shandong Normal University, Ji'nan 250014, China;
2. School of Environmental Science and Engineering, Shandong University, Qingdao 266237, China;
3. College of Safety and Environmental Engineering, Shandong University of Science and Technology, Qingdao 266590, China;
4. College of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University, Ji'nan 250014, China

摘要

摘要: 人工湿地是区域再生水循环利用的重要技术手段，具有绿色低碳、经济成本低等优点，能有效去除抗生素。然而，抗生素在人工湿地的去除并不意味着生态风险的同步削减，其微生物转化过程可能形成具有更高毒性的转化产物，从而产生潜在的二次环境风险。针对上述问题，系统总结了人工湿地中抗生素的主要去除途径，重点梳理了不同类型抗生素在人工湿地的典型微生物转化路径、产物形成特征与潜在生态风险，详细分析了溶解氧、水力停留时间、温度、基质类型和湿地构型等设计、运行参数对抗生素转化的调控作用，提出了实现抗生素安全转化的强化型人工湿地技术，并对抗生素转化产物的复合污染协同控制、耐药选择机制解析及风险评价体系构建等未来研究方向进行展望。
- 人工湿地 /
- 抗生素 /
- 转化产物 /
- 转化路径 /
- 安全转化
Abstract: Constructed wetlands are an important technological approach for regional reclaimed water recycling and reuse， offering advantages such as low carbon emissions and low economic costs while effectively removing antibiotics. However， the removal of antibiotics in constructed wetlands does not necessarily imply a corresponding reduction in ecological risks， as microbial transformation may generate transformation products with higher toxicity， which may pose secondary environmental risks. To address these concerns， this review systematically summarizes the major removal pathways of antibiotics in constructed wetlands， with particular emphasis on the typical microbial transformation pathways， product formation characteristics， and potential ecological risks of different antibiotic classes. It further analyzes in detail the regulatory effects of design and operational parameters， including dissolved oxygen， hydraulic retention time， temperature， substrate type， and wetland configuration， on antibiotic transformation. In addition， enhanced constructed wetland technologies for achieving the safe transformation of antibiotics are proposed， and future research directions are discussed， including the synergistic control of co-contamination involving antibiotic transformation products， the elucidation of antibiotic resistance selection mechanisms， and the development of comprehensive risk assessment frameworks.
- constructed wetlands /
- antibiotics /
- transformation product /
- transformation pathway /
- safe transformation

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